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Article

Role of myeloid cells in mediating the effects of lipids on ulcerative colitis.

Frontiers in immunology - 1 Jan 2024

Xiao Jinyin, Guo Xiajun, Li Keya, Luo Wenpeng, Lin Youwei, Lu Wenhong, Wang Zhenquan

Abstract excerpt

Objective: To evaluate the causal relationship between lipids and ulcerative colitis (UC) through Mendelian Randomization (MR), and to further investigate the involvement of immune cells in mediating this process. Methods: Utilizing summary statistics from genome-wide association studies (GWAS) of individuals with European ancestry, we analyzed the causal link between 179 lipid types and UC (2,569 UC cases and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39286250
DOI: 10.3389/fimmu.2024.1416562
PMCID: PMC11402659

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