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Article

Plasma lipid species, immune cell traits, and gastric cancer risk: A Mendelian randomization study.

Medicine - 11 Sept 2026

Huang Peng, Yu Tianqi, Wang Lei, Zhou Yongxu

Abstract excerpt

Plasma lipid composition has been linked to multiple cancers, yet its causal contribution to gastric cancer and the potential intermediary role of immune cells remain unclear. We aimed to clarify these relationships and identify specific lipid and immune cell traits that either protect against or promote gastric cancer. We performed a 2-sample, 2-step Mendelian randomization analysis using summary statistics from...

Read the complete abstract on PubMed

Topics

Humans
Stomach Neoplasms
Mendelian Randomization Analysis
Genome-Wide Association Study
Lipids
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Lipidomics

Phosphatidylcholines

Risk Factors

Genetic Predisposition to Disease

Phosphatidylethanolamines

Source

Open in PubMed Open full text

Identifiers

PMID: 42736747
DOI: 10.1097/MD.0000000000050371
PMCID: PMC13574483

Genes

CD28
CD4
CCR2
CD14
CD19
CD38

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

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