Article
Sequence-based CYP2D6 genotyping in the Korean population.
Therapeutic drug monitoring - 1 Jun 2006
Lee Soo-Youn, Sohn Kwang Min, Ryu Ji Young, Yoon Young Ran, Shin Jae Gook, Kim Jong-Won
Abstract excerpt
For clinical application of pharmacogenetic tests, quantitative prediction of enzyme activity based on accurate determination of genotype is essential. There has been limited information available on the genetic polymorphism of CYP2D6 in the Korean population. In this study, CYP2D6 genotypes were assessed in 400 Korean subjects. Twenty-eight different CYP2D6 alleles and 35 genotypes were detected. On the basis of...
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