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Article

Neurostructural Correlates of Polygenic Risk for Coronary Artery Disease in Relation to Youth Bipolar Disorder.

Bipolar disorders - 1 Dec 2025

Kulkarni Nidhi P, Zai Clement C, Kennedy Kody G, Mio Megan, Young L Trevor, MacIntosh Bradley J, Goldstein Benjamin I

Abstract excerpt

INTRODUCTION: Bipolar disorder (BD), characterized by anomalous neurostructural phenotypes, is also strongly associated with cardiovascular disease. Here we examined polygenic risk for coronary artery disease (CAD) in relation to gray matter structure in youth BD. METHODS: Youth participants (mean age 17.1 years; n = 66 BD, n = 45 healthy controls [HC]) underwent T1-weighted magnetic resonance imaging. CAD...

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Identifiers

PMID: 40994160
DOI: 10.1111/bdi.70065
PMCID: PMC12706564

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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