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Genomic insights on lung cancer risk: identifying new variants in Amazonian indigenous populations.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Feb 2026

Fernandes Bruno Melo, da Costa Ana Caroline Alves, Monte Natasha, Aguiar Kaio Evandro Cardoso, Santo Marcella Oliveira Monte, Rodrigues Juliana Carla Gomes, Pereira Esdras Edgar Batista, Guerreiro João Farias, Dos Santos Sidney Emanuel Batista, Ribeiro-Dos-Santos Ândrea, Ribeiro-Dos-Santos André Maurício, Burbano Rommel Mario Rodríguez, Fernandes Marianne Rodrigues, Dos Santos Ney Pereira Carneiro

Abstract excerpt

INTRODUCTION: Significant progress has been made in understanding and treating lung cancer. In the unique context of the Amazonian indigenous population, it is crucial to identify genetic variants in genes important for the risk of developing this cancer. There is a limitation of research on the broader genomic profile of indigenous peoples, especially in the Amazon region, in relation to lung cancer. METHODS: We...

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PMID: 40875182
DOI: 10.1007/s12094-025-04033-6

Genes

ERBB2
KRAS
RET
BRAF
MET

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