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Article

A Pilot Study: Contrasting Genomic Profiles of Lung Adenocarcinoma Between Patients of European and Latin American Ancestry.

International journal of molecular sciences - 19 May 2025

Rueda-Zarazua Bertha, Gutiérrez Humberto, García-Ortiz Humberto, Orozco Lorena, Ramírez-Martínez Gustavo, Jiménez-Alvarez Luis, Bolaños-Morales Francina V, Zuñiga Joaquín, Ávila-Moreno Federico, Melendez-Zajgla Jorge

Abstract excerpt

Lung cancer remains as the leading cause of cancer mortality worldwide. However, while current evidence suggests the existence of genomic differences between populations, indicating different risk factors associated with population-level genetic backgrounds, most studies have concentrated on populations of European ancestry, and more research is needed on non-European populations. We analyzed whole-exome...

Read the complete abstract on PubMed

Topics

Adult
Aged
Female
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Adenocarcinoma of Lung

Exome Sequencing

Genetic Predisposition to Disease

Genomics

Latin America

Lung Neoplasms

Mexico

Mutation

Pilot Projects

Smoking

White People

Source

Open in PubMed Open full text

Identifiers

PMID: 40430005
DOI: 10.3390/ijms26104865
PMCID: PMC12111962

Genes

AP1S1
SLC36A4
TP53

Provenance

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