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The Multifaceted Role of p53 in Cancer Molecular Biology: Insights for Precision Diagnosis and Therapeutic Breakthroughs

27 Jul 2025

Abstract excerpt

The protein p53, often referred to as the "guardian of the genome," is essential for preserving cellular balance and preventing cancerous transformations. As one of the most commonly altered genes in human cancers, its impaired function is associated with tumor initiation, development, and resistance to treatment. Exploring the diverse roles of p53, which include regulating the cell cycle, repairing DNA, inducing...

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PMID: 40867533
DOI: 10.3390/biom15081088

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