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Mathematical model of replication–mutation dynamics in coronaviruses

18 Aug 2025

Abstract excerpt

RNA viruses are known for their fascinating evolutionary dynamics, characterised by high mutation rates, fast replication, and ability to form quasispecies - clouds of genetically related mutants. Fast replication in RNA viruses is achieved by a very fast but error-prone RNA-dependent RNA polymerase (RdRP). High mutation rates are a double-edged sword: they provide RNA viruses with a mechanism of fast adaptation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40835088
DOI: 10.1016/j.mbs.2025.109518

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