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Article

Puzzles, challenges, and information reservoir of SARS-CoV-2 quasispecies

21 Nov 2023

Abstract excerpt

Upon the emergence of SARS-CoV-2 in the human population, it was conjectured that for this coronavirus the dynamic intra-host heterogeneity typical of RNA viruses would be toned down. Nothing of this sort is observed. Here we review the main observations on the complexity and diverse composition of SARS-CoV-2 mutant spectra sampled from infected patients, within the framework of quasispecies dynamics. The...

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PMID: 38092661
DOI: 10.1128/jvi.01511-23

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