Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An Aberrant Resurgence of Endogenous Retroviruses Prompts Myocarditis and Heart Failure

18 Aug 2025

Abstract excerpt

BACKGROUND: Endogenous retroviruses (ERVs) occupy >8% of the human genome. Aberrant resurgence of ERVs has been implicated recently in several critical pathologies. However, the possible incidence and role of ERV resurgence in heart failure (HF), a leading cause of global morbidity and mortality, remain unexplored. METHODS: We established a total RNA sequencing analyzing pipeline to assess the ERV occurrence in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomal and Genetic Variations
Share to Herpesvirus Infections and Treatments
Share to Xenotransplantation and immune response

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40820798
DOI: 10.1161/circulationaha.125.074845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An Aberrant Resurgence of Endogenous Retroviruses Prompts Myocarditis and Heart FailurePMID 40820798Read ↗

Spatiotemporal transcriptomics reveals pathogenesis of viral myocarditisSemantic proximity Read ↗

Cardiac SARS-CoV-2 infection is associated with pro-inflammatory transcriptomic alterations within the heartSemantic proximity Read ↗

Spatiotemporal transcriptomics reveals pathogenesis of viral myocarditisSemantic proximity Read ↗

Human influenza A virus causes myocardial and cardiac-specific conduction system infections associated with early inflammation and premature death.Semantic proximity Read ↗

Cardiac SARS-CoV-2 infection is associated with distinct transcriptomic changes within the heartSemantic proximity Read ↗

Discovery of miRNAs Unique to Actively Transcribed Erythroparvovirus Infection in Heart Failure PatientsSemantic proximity Read ↗

Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human PrimatesSemantic proximity Read ↗

Dissecting the cellular landscape and transcriptome network in viral myocarditis by single-cell RNA sequencingSemantic proximity Read ↗

Influenza virus replication in cardiomyocytes drives heart dysfunction and fibrosisSemantic proximity Read ↗

Macrophage-derived SPP1 exacerbate myocardial injury by interacting with fibroblasts in viral myocarditisSemantic proximity Read ↗

Mechanisms of Innate Immune Injury in Arrhythmogenic CardiomyopathySemantic proximity Read ↗

Underdiagnosed Viral Infections in Heart Failure: Metagenomic Sequencing Reveals Association with Left Ventricular DysfunctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.