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Article

Cardiac SARS-CoV-2 infection is associated with pro-inflammatory transcriptomic alterations within the heart

13 Oct 2021

Abstract excerpt

AIMS: Cardiac involvement in COVID-19 is associated with adverse outcome. However, it is unclear whether cell-specific consequences are associated with cardiac SARS-CoV-2 infection. Therefore, we investigated heart tissue utilizing in situ hybridization, immunohistochemistry, and RNA-sequencing in consecutive autopsy cases to quantify virus load and characterize cardiac involvement in COVID-19. METHODS AND...

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PMID: 34647998
DOI: 10.1093/cvr/cvab322

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