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Underdiagnosed Viral Infections in Heart Failure: Metagenomic Sequencing Reveals Association with Left Ventricular Dysfunction

2025-11-17

Abstract excerpt

<h4>BACKGROUND</h4> Viral infections are a major cause of inflammatory heart disease, but conventional polymerase chain reaction (PCR) often fails to detect the causative pathogens, limiting diagnostic and therapeutic decisions. We investigated whether targeted metagenomic next-generation sequencing (NGS) improves virus detection in endomyocardial biopsies (EMB) compared to standard PCR, and examined the clinical...

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Literature Corpus work
8d604231-9e71-5c0b-a02c-ae29a9648ff2
DOI
10.1101/2025.11.11.25339799
Open publication

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Underdiagnosed Viral Infections in Heart Failure: Metagenomic Sequencing Reveals Association with Left Ventricular DysfunctionDOI 10.1101/2025.11.11.25339799
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