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Article

SERPINA1 Gene Variants in Granulomatosis with Polyangiitis.

Advances in experimental medicine and biology - 1 Jan 2018

Hadzik-Blaszczyk Malgorzata, Zdral Aneta, Zielonka Tadeusz M, Rozy Ada, Krupa Renata, Falkowski Andrzej, Wardyn Kazimierz A, Chorostowska-Wynimko Joanna, Zycinska Katarzyna

Abstract excerpt

Alpha-1 antitrypsin (A1AT) deficiency is one of the most common genetic disorders in Caucasian population. There is a link between granulomatosis with polyangiitis (GPA) and most frequent variants of SERPINA1 gene encoding severe alpha-1 antitripsin deficiency. However, the potential effect of Pi*Z, Pi*S as well as other SERPINA1 variants on clinical course of vasculitis are not well understood. The aim of the...

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PMID: 29460271
DOI: 10.1007/5584_2018_156

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SERPINA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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