The states of senescent cells

Abstract excerpt

Senescent cells (SnCs) have typical changes in multiple features, such as increased cellular and nuclear size, morphofunctional alterations in organelles, and high secretory activity. The literature generally groups cellular changes and the non-proliferative character of SnCs into the autonomous senescent phenotype. In contrast, the influence of molecules and extracellular vesicles secreted by SnCs characterizes...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetics, Aging, and Longevity in Model Organisms
• Share to Single-cell and spatial transcriptomics
• Share to Telomeres, Telomerase, and Senescence