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Cellular senescence in reproduction: a two-edged sword†.

Biology of reproduction - 11 Apr 2024

Pretto Luiza, Nabinger Eduarda, Filippi-Chiela Eduardo Cremonesi, Fraga Lucas Rosa

Abstract excerpt

Cellular senescence (CS) is the state when cells are no longer capable to divide even after stimulation with grown factors. Cells that begin to undergo CS stop in the cell cycle and enter a suspended state without committing to programmed cell death. These cells assume a specific phenotype and influence their microenvironment by secreting molecules and extracellular vesicles that are part of the so-called...

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PMID: 38480995
DOI: 10.1093/biolre/ioae025

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