Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Mutation in the RNA-Binding Protein Cth2 Limits the Adaptation of a Subset of Wild Saccharomyces cerevisiae Yeast Strains to Iron Deficiency.

Molecular and cellular biology - 1 Jan 2025

Valera-García Elena, Sorribes-Dauden Raquel, Puig Sergi

Abstract excerpt

Iron is an essential micronutrient for eukaryotic organisms. In response to iron deficiency, the yeast Saccharomyces cerevisiae optimizes iron utilization by downregulating nonessential iron-dependent processes, such as mitochondrial respiration. This regulatory mechanism is mediated by a mRNA-binding protein designated Cth2. In response to iron scarcity, Cth2 binds through its tandem zinc-finger (TFZ) domain to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Gene Expression Regulation, Fungal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Iron Deficiencies

Share to RNA-Binding Proteins

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to Zinc Fingers

Source

Identifiers

PMID: 40757737
DOI: 10.1080/10985549.2025.2539754

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Mutation in the RNA-Binding Protein Cth2 Limits the Adaptation of a Subset of Wild Saccharomyces cerevisiae Yeast Strains to Iron Deficiency.PMID 40757737Read ↗

Coordinated remodeling of cellular metabolism during iron deficiency through targeted mRNA degradation.Semantic proximity Read ↗

The Cth2 ARE-binding protein recruits the Dhh1 helicase to promote the decay of succinate dehydrogenase SDH4 mRNA in response to iron deficiency.Semantic proximity Read ↗

<i>C. elegans</i> TFIIH subunit GTF-2H5/TTDA is a non-essential transcription factor indispensable for DNA repairSemantic proximity Read ↗

Cti6 is an Rpd3-Sin3 histone deacetylase-associated protein required for growth under iron-limiting conditions in Saccharomyces cerevisiae.Semantic proximity Read ↗

Transcriptome profiling of Saccharomyces cerevisiae mutants lacking C2H2 zinc finger proteins.Semantic proximity Read ↗

Molecular strategies to increase yeast iron accumulation and resistance.Semantic proximity Read ↗

Motifs in the histone H3 and H4 and chromatin modifying factors are crucial to regulate the multifactorial zinc response pathway in Saccharomyces cerevisiae.Semantic proximity Read ↗

The ZRT2 gene encodes the low affinity zinc transporter in Saccharomyces cerevisiae.Semantic proximity Read ↗

Genome-wide analysis of iron-dependent growth reveals a novel yeast gene required for vacuolar acidification.Semantic proximity Read ↗

A second iron-regulatory system in yeast independent of Aft1p.Semantic proximity Read ↗

Post-transcriptional regulation of transcript abundance by a conserved member of the tristetraprolin family in Candida albicans.Semantic proximity Read ↗

The mRNAs associated to a zinc finger protein fromTrypanosoma cruzishift during stress conditionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.