Article
Molecular strategies to increase yeast iron accumulation and resistance.
Metallomics : integrated biometal science - 19 Sept 2018
Ramos-Alonso Lucía, Wittmaack Nadine, Mulet Isabel, Martínez-Garay Carlos A, Fita-Torró Josep, Lozano María Jesús, Romero Antonia M, García-Ferris Carlos, Martínez-Pastor María Teresa, Puig Sergi
Abstract excerpt
All eukaryotic organisms rely on iron as an essential micronutrient for life because it participates as a redox-active cofactor in multiple biological processes. However, excess iron can generate reactive oxygen species that damage cellular macromolecules. The low solubility of ferric iron under physiological conditions increases the prevalence of iron deficiency anemia. A common strategy to treat iron deficiency...
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