Article
Post-transcriptional regulation of transcript abundance by a conserved member of the tristetraprolin family in Candida albicans.
Molecular microbiology - 1 Mar 2015
Wells Melissa L, Washington Onica L, Hicks Stephanie N, Nobile Clarissa J, Hartooni Nairi, Wilson Gerald M, Zucconi Beth E, Huang Weichun, Li Leping, Fargo David C, Blackshear Perry J
Abstract excerpt
Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger proteins bind to AU-rich regions in target mRNAs, leading to their deadenylation and decay. Family members in Saccharomyces cerevisiae influence iron metabolism, whereas the single protein expressed in Schizosaccharomyces pomb...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
