The effect of PU/MWCNT nanofiber scaffolds containing hesperidin nanoparticles and mesenchymal stem cells on the microglia and astrocyte phenotype in the spinal cord injury model.

Abstract excerpt

Spinal cord injury (SCI) is a neurodegenerative disease involving inflammation, microgliosis, and astrocytosis. This study examined how polyurethane/multi-walled carbon nanotube (PU/MWCNT) nanofiber scaffolds containing hesperidin nanoparticles (NPs) and adipose-derived mesenchymal stem cells (AMSCs) affect the phenotype of microglia and astrocytes in an SCI model. Thirty-six male rats were divided into six...

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