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Article

Effect of Myelin Debris on the Phenotypic Transformation of Astrocytes after Spinal Cord Injury in Rats.

Neuroscience - 24 May 2024

Lv Jianwei, Yu Hang, Shan Fangli, Ye Jianan, Li Ao, Jing Juehua, Zheng Meige, Tian Dasheng

Abstract excerpt

After spinal cord injury (SCI), the accumulation of myelin debris can serve as proinflammatory agents, hindering axon regrowth and exacerbating damage. While astrocytes have been implicated in the phagocytosis of myelin debris, the impact of this process on the phenotypic transformation of astrocytes and their characteristics following SCI in rats is not well understood. Here, we demonstrated that the conditioned...

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Identifiers

PMID: 38570063
DOI: 10.1016/j.neuroscience.2024.03.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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