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ctDNA methylation profiling reveals NBL1 as a promising biomarker for early ovarian cancer screening

28 Jul 2025

Abstract excerpt

BACKGROUND: Early detection of epithelial ovarian cancer (EOC) is crucial for improving patient survival. Current screening methods have limitations, highlighting the need for novel biomarkers. Circulating tumor DNA (ctDNA) methylation analysis offers a promising approach. METHODS: This study included 10 patients with EOC and 10 patients with benign pelvic masses. We collected plasma samples from these patients...

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PMID: 40722077
DOI: 10.1186/s12957-025-03957-1

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