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Article

An epigenetic signature in peripheral blood predicts active ovarian cancer.

PloS one - 18 Dec 2009

Teschendorff Andrew E, Menon Usha, Gentry-Maharaj Aleksandra, Ramus Susan J, Gayther Simon A, Apostolidou Sophia, Jones Allison, Lechner Matthias, Beck Stephan, Jacobs Ian J, Widschwendter Martin

Abstract excerpt

BACKGROUND: Recent studies have shown that DNA methylation (DNAm) markers in peripheral blood may hold promise as diagnostic or early detection/risk markers for epithelial cancers. However, to date no study has evaluated the diagnostic and predictive potential of such markers in a large case control cohort and on a genome-wide basis. PRINCIPAL FINDINGS: By performing genome-wide DNAm profiling of a large ovarian...

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Identifiers

PMID: 20019873
DOI: 10.1371/journal.pone.0008274
PMCID: PMC2793425

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Source receipt: pubmed, retrieved 7 Sept 2026.

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