Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of Methylation Biomarkers for Detection of Circulating Tumor DNA and Application to Colorectal Cancer

15 Dec 2016

Abstract excerpt

Solid tumors shed DNA into circulation, and there is growing evidence that the detection of circulating tumor DNA (ctDNA) has broad clinical utility, including monitoring of disease, prognosis, response to chemotherapy and tracking tumor heterogeneity. The appearance of ctDNA in the circulating cell-free DNA (ccfDNA) isolated from plasma or serum is commonly detected by identifying tumor-specific features such as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Epigenetics and DNA Methylation
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27983717
DOI: 10.3390/genes7120125

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of Methylation Biomarkers for Detection of Circulating Tumor DNA and Application to Colorectal CancerPMID 27983717Read ↗

Mutation-Agnostic Detection of Colorectal Cancer Using Liquid Biopsy-Based Methylation-Specific Signatures.Semantic proximity Read ↗

Discovery and Validation of Methylation Signatures in Circulating Cell-Free DNA for the Detection of Colorectal CancerSemantic proximity Read ↗

Evaluation of an assay for methylated BCAT1 and IKZF1 in plasma for detection of colorectal neoplasiaSemantic proximity Read ↗

Methylated circulating tumor DNA in blood: power in cancer prognosis and responseSemantic proximity Read ↗

Evaluation of a panel of tumor-specific differentially-methylated DNA regions in IRF4, IKZF1 and BCAT1 for blood-based detection of colorectal cancerSemantic proximity Read ↗

A Two-Gene Blood Test for Methylated DNA Sensitive for Colorectal CancerSemantic proximity Read ↗

A new approach to epigenome-wide discovery of non-invasive methylation biomarkers for colorectal cancer screening in circulating cell-free DNA using pooled samplesSemantic proximity Read ↗

Quantification method of ctDNA using cell-free DNA methylation profile for noninvasive screening and monitoring of colon cancerSemantic proximity Read ↗

Methylated circulating tumor DNA as a biomarker for colorectal cancer diagnosis, prognosis, and predictionSemantic proximity Read ↗

DNA Methylation Patterns as Noninvasive Biomarkers and Targets of Epigenetic Therapies in Colorectal CancerSemantic proximity Read ↗

Discovery and validation of methylation signatures in blood-based circulating tumor cell-free DNA in early detection of colorectal carcinoma: a case–control studySemantic proximity Read ↗

Novel DNA methylation biomarkers show high sensitivity and specificity for blood-based detection of colorectal cancer—a clinical biomarker discovery and validation studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.