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Article

Clinical and genetic predictors of renal dysfunctions in sickle cell anaemia in Cameroon.

British journal of haematology - 1 Aug 2017

Geard Amy, Pule Gift D, Chetcha Chemegni Bernard, Ngo Bitoungui Valentina J, Kengne Andre P, Chimusa Emile R, Wonkam Ambroise

Abstract excerpt

Micro-albuminuria and glomerular hyperfiltration are primary indicators of renal dysfunctions in Sickle Cell Disease (SCD), with more severe manifestations previously associated with variants in APOL1 and HMOX1 among African Americans. We have investigated 413 SCD patients from Cameroon. Anthropometric variables, haematological indices, crude albuminuria, albumin-to-creatinine ratio (ACR) and estimated glomerular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28466968
DOI: 10.1111/bjh.14724
PMCID: PMC5660286

Genes

APOL1
HMOX1
SCD
ACR
HBA1
HBA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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