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Human Genetics Informing Drug Development in Cardiovascular Disease: Interleukin-6 Signaling as a Case Study

28 Jul 2025

Abstract excerpt

Cardiovascular disease remains the leading cause of death worldwide, calling for the development of novel therapeutics. Over the past 3 decades, substantial investments in human genetic research have unveiled the genetic architecture of cardiovascular disease, offering promising novel therapeutic targets. These discoveries have been instrumental in the development of several cardiovascular drug development...

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PMID: 40718904
DOI: 10.1161/circgen.125.005103

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