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Article

Evaluation of the circulating levels of IL-33 in patients with osteoarthritis: role of rs1929992 variants.

Cytokine - 1 Oct 2025

Alimoradi Nahid, Jahankhah Fatemeh, Jokardarzi Habibollah, Tahami Mohammad, Firouzabadi Negar

Abstract excerpt

BACKGROUND: Osteoarthritis (OA) is among the common chronic health conditions which impacts many aspects of an individual's life from physical function to mental health. Inflammation, in the joint as well as system inflammation is among the many mechanisms hypothesized to be involved in OA. IL-33 which belongs to the IL-1 family, is considered as an alarmin in OA. IL-33 binds to a group of receptors to stimulate...

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PMID: 40712435
DOI: 10.1016/j.cyto.2025.156996

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