Article
The association of novel IL-33 polymorphisms with sIL-33 and risk of systemic lupus erythematosus.
Molecular immunology - 1 Sept 2016
Guo Jing, Xiang Yang, Peng You-Fan, Huang Hua-Tuo, Lan Yan, Wei Ye-Sheng
Abstract excerpt
The serum level of IL-33 was upregulated in systemic lupus erythematosus (SLE), which may be used as biomarkers and/or therapeutic targets for SLE. The aim of this study was to investigate the association of four novel polymorphisms of IL-33 with risk of SLE. The study population comprised 540 Chinese individuals, including 257subjects with SLE and 283 healthy controls. The gene polymorphism was measured using...
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