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HIV Integration into the PTEN Gene and Its Tumor Microenvironment Implications for Lung Cancer

4 Jul 2025

Abstract excerpt

Health outcomes for people with HIV (PWH) have improved significantly with combination antiretroviral therapy (ART), yet the risk of lung cancer remains elevated. While a single case cannot establish causality, we describe here an investigation of a 74-year-old male PWH with de novo high-grade neuroendocrine small cell lung carcinoma. To investigate the potential contribution of HIV to cancer development, we...

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PMID: 40710199
DOI: 10.3390/curroncol32070389

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