Article
Characterization of the genomic landscape of HIV-associated lymphoma reveals heterogeneity across histological subtypes.
AIDS (London, England) - 15 Nov 2024
Hybel Trine Engelbrecht, Sørensen Emma Frasez, Enemark Marie Hairing, Hemmingsen Jonas Klejs, Simonsen Anita Tranberg, Lauridsen Kristina Lystlund, Møller Michael Boe, Pedersen Court, Pedersen Gitte, Obel Niels, Larsen Carsten Schade, d'Amore Francesco, Hamilton-Dutoit Stephen, Stougaard Magnus, Vase Maja Ølholm, Ludvigsen Maja
Abstract excerpt
OBJECTIVE: Individuals with HIV experience an increased risk of lymphoma, making this an important cause of death among people with HIV. Nevertheless, little is known regarding the underlying genetic aberrations, which we therefore set out to characterize. DESIGN: We conducted next-generation panel sequencing to explore the mutational status of diagnostic lymphoma biopsies from 18 patients diagnosed with lymphoma...
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