Article
Molecular profiling of breast and lung cancer in women with HIV reveals high tumor mutational burden.
AIDS (London, England) - 15 Mar 2022
Caro-Vegas Carolina, Ramirez Catalina, Landis Justin, Adimora Adaora A, Strickler Howard, French Audrey L, Ofotokun Igho, Fischl Margaret, Seaberg Eric C, Wang Chia-Ching J, Spence Amanda B, Dittmer Dirk P
Abstract excerpt
OBJECTIVE: This study compared the mutation profile and tumor mutational burden (TMB) in women with HIV (WWH) diagnosed with lung adenocarcinoma (n = 8) or breast ductal neoplasm (n = 13) who were enrolled into the Women's Interagency HIV Study (WIHS). DESIGN: Previous studies tended to focus on single institutions based on sample availability. This study is based on a representative, multicenter cohort that...
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