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Article

Activating Cancer Hallmarks through Changes in mRNA/Protein Regulation.

Journal of proteome research - 1 Aug 2025

Giraldez Chavez Jose Humberto, Barton Nathaniel, Lindgren Caleb M, Mendenhall Bryn, Kimball Benjamin, Payne Samuel H

Abstract excerpt

As a diverse family of diseases, cancer is unified by a set of common dysfunctions, such as limitless growth potential and an insensitivity to antigrowth signals. These shared overarching biological processes have been termed the hallmarks of cancer. To better understand the root cause of cellular dysregulation, intense molecular characterization of tumors has utilized DNA, RNA, and protein measurement techniques...

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Identifiers

PMID: 40674356
DOI: 10.1021/acs.jproteome.4c00284
PMCID: PMC12322998

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