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The functional cancer map: A systems-level synopsis of genetic deregulation in cancer

30 Jun 2011

Abstract excerpt

BACKGROUND: Cancer cells are characterized by massive dysegulation of physiological cell functions with considerable disruption of transcriptional regulation. Genome-wide transcriptome profiling can be utilized for early detection and molecular classification of cancers. Accurate discrimination of functionally different tumor types may help to guide selection of targeted therapy in translational research. Concise...

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PMID: 21718500
DOI: 10.1186/1755-8794-4-53

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