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Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways

13 May 2022

Abstract excerpt

Mass-spectrometry-based proteomic data on human tumors-combined with corresponding multi-omics data-present opportunities for systematic and pan-cancer proteogenomic analyses. Here, we assemble a compendium dataset of proteomics data of 2002 primary tumors from 14 cancer types and 17 studies. Protein expression of genes broadly correlates with corresponding mRNA levels or copy number alterations (CNAs) across...

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PMID: 35562349
DOI: 10.1038/s41467-022-30342-3

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