Article
Methylation-based smoking signatures in blood and tissue samples for the prediction of self-reported smoking status and mortality in patients with colorectal cancer
3 Jul 2025
Abstract excerpt
BACKGROUND: Smoking is a well-established risk factor for colorectal cancer (CRC) development. However, the reliability of DNA methylation-based smoking signatures in predicting smoking status and their prognostic value in CRC remain unclear, particularly across different biological sample types. RESULTS: Five previously validated methylation-based smoking signatures were analyzed in 2237 CRC patients with...
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