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Discovery and validation of tissue-specific DNA methylation as noninvasive diagnostic markers for colorectal cancer

16 Aug 2022

Abstract excerpt

BACKGROUND: Noninvasive diagnostic markers that are capable of distinguishing patients with colorectal cancer (CRC) from healthy individuals or patients with other cancer types are lacking. We report the discovery and validation of a panel of methylation-based markers that specifically detect CRC. METHODS: This was a large-scale discovery study based on publicly available datasets coupled with a validation study...

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Share to Colorectal Cancer Screening and Detection
Share to Epigenetics and DNA Methylation
Share to Genetic factors in colorectal cancer

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PMID: 35974349
DOI: 10.1186/s13148-022-01312-9

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