Article
A panel of DNA methylation signature from peripheral blood may predict colorectal cancer susceptibility.
BMC cancer - 25 Jul 2020
Onwuka Justina Ucheojor, Li Dapeng, Liu Yupeng, Huang Hao, Xu Jing, Liu Ying, Zhang Yuanyuan, Zhao Yashuang
Abstract excerpt
BACKGROUND: Differential DNA methylation panel derived from peripheral blood could serve as biomarkers of CRC susceptibility. However, most of the previous studies utilized post-diagnostic blood DNA which may be markers of disease rather than susceptibility. In addition, only a few studies have evaluated the predictive potential of differential DNA methylation in CRC in a prospective cohort and on a genome-wide...
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