Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection.

Cell reports. Medicine - 18 May 2021

Rouers Angeline, Chng Melissa Hui Yen, Lee Bernett, Rajapakse Menaka P, Kaur Kaval, Toh Ying Xiu, Sathiakumar Durgalakshmi, Loy Thomas, Thein Tun-Linn, Lim Vanessa W X, Singhal Amit, Yeo Tsin Wen, Leo Yee-Sin, Vora Kalpit A, Casimiro Danilo, Lim Bing, Tucker-Kellogg Lisa, Rivino Laura, Newell Evan W, Fink Katja

Abstract excerpt

Prior immunological exposure to dengue virus can be both protective and disease-enhancing during subsequent infections with different dengue virus serotypes. We provide here a systematic, longitudinal analysis of B cell, T cell, and antibody responses in the same patients. Antibody responses as well as T and B cell activation differentiate primary from secondary responses. Hospitalization is associated with lower...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Neutralizing
Share to Antibodies, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cross Reactions

Share to Dengue

Share to Dengue Virus

Share to Plasma Cells

Share to Serogroup

Source

Open in PubMed Open full text

Identifiers

PMID: 34095880
DOI: 10.1016/j.xcrm.2021.100278
PMCID: PMC8149372

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection.PMID 34095880Read ↗

Immune profiling in subclinical secondary dengue-infected cases reveals adaptive immune signatures correlated to protection from severe dengueSemantic proximity Read ↗

Dengue virus-specific memory B cell subsets differ as a function of infection historySemantic proximity Read ↗

Global and cell type-specific immunological hallmarks of severe dengue progressionSemantic proximity Read ↗

Quantification of dengue virus specific T cell responses and correlation with viral load and clinical disease severity in acute dengue infectionSemantic proximity Read ↗

Plasmablasts During Acute Dengue Infection Represent a Small Subset of a Broader Virus-specific Memory B Cell Pool.Semantic proximity Read ↗

Evolution of inflammation and immunity in a dengue virus 1 human infection modelSemantic proximity Read ↗

Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19Semantic proximity Read ↗

Transcriptomics of Acute DENV-Specific CD8+ T Cells Does Not Support Qualitative Differences as Drivers of Disease SeveritySemantic proximity Read ↗

Factors affecting plasma viremia and host immune responses in dengue infectionSemantic proximity Read ↗

Understanding the contribution of cellular immunity to dengue disease pathogenesisSemantic proximity Read ↗

Integrated single-cell analysis reveals interferon-driven immune signatures in a DENV1 human infection modelSemantic proximity Read ↗

Phenotype and functionality of follicular helper T cells in patients with acute dengue infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.