Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations of healthy lifestyle and genetic susceptibility with risks of osteoarthritis: a prospective cohort study.

Rheumatology (Oxford, England) - 1 Nov 2025

Chen Shibo, Zhang Yujie, Fan Tianxiang, Zeng Muhui, Yang Qian, Yang Hao, Fang Xiaofeng, Jin Xingzhong, Cao Peihua, Wang Zhiqiang, Zhang Yan, Hunter David J, Zhou Yuan, Ding Changhai, Zhu Zhaohua

Abstract excerpt

OBJECTIVES: To detect the associations of a healthy lifestyle and genetic susceptibility with incident OA in the UK Biobank study. METHODS: We included 314 729 participants from UK Biobank. Five modifiable lifestyle factors including weight management, diet, physical activity, sleep behaviour and sedentary behaviour were included to generate an overall lifestyle score. Genetic susceptibility was calculated by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exercise
Share to Healthy Lifestyle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Incidence

Share to Osteoarthritis

Share to Osteoarthritis, Hip

Share to Osteoarthritis, Knee

Share to Sedentary Behavior

Share to United Kingdom

Source

Identifiers

PMID: 40578805
DOI: 10.1093/rheumatology/keaf327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations of healthy lifestyle and genetic susceptibility with risks of osteoarthritis: a prospective cohort study.PMID 40578805Read ↗

Physical activity patterns, genetic susceptibility, and risk of hip/knee osteoarthritis: a prospective cohort study based on the UK Biobank.Semantic proximity Read ↗

The Genetic Epidemiological Landscape of Hip and Knee Osteoarthritis: Where Are We Now and Where Are We Going?Semantic proximity Read ↗

Ultra-processed food consumption, genetic susceptibility, and the risk of hip/knee osteoarthritis.Semantic proximity Read ↗

Associations of Healthy Lifestyles with All-Cause Mortality Among Individuals with Osteoarthritis: Results from UK Biobank and US NHANESSemantic proximity Read ↗

Association of genetic risk, lifestyle, and their interaction with obesity and obesity-related morbidities.Semantic proximity Read ↗

Healthy lifestyle counteracts the risk effect of genetic factors on incident gout: a large population-based longitudinal study.Semantic proximity Read ↗

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.Semantic proximity Read ↗

Association of Healthy Lifestyle with the Incidence of the Risk of Developing a Broad Range of Diseases: A Prospective Cohort StudySemantic proximity Read ↗

The genetic architecture of osteoarthritis: insights from UK BiobankSemantic proximity Read ↗

Cardiometabolic traits mediating the effect of education on osteoarthritis risk: a Mendelian randomization studySemantic proximity Read ↗

Cardiovascular risk according to genetic predisposition to gout, lifestyle and metabolic health across prospective European and Korean cohorts.Semantic proximity Read ↗

Data-driven identification of predictive risk biomarkers for subgroups of osteoarthritis using an interpretable machine learning framework: a UK biobank studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.