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Article

Healthy lifestyle counteracts the risk effect of genetic factors on incident gout: a large population-based longitudinal study.

BMC medicine - 29 Apr 2022

Zhang Yuan, Yang Rongrong, Dove Abigail, Li Xuerui, Yang Hongxi, Li Shu, Wang Ju, Li Wei-Dong, Zhao Hongyu, Xu Weili, Wang Yaogang

Abstract excerpt

BACKGROUND: Risk genes linked to the development of gout have been identified, and lifestyle factors are related to gout risk. It remains unclear whether healthy lifestyle factors can mitigate the genetic risk of gout. Therefore, we aimed to explore whether and to what extent a healthy lifestyle can mitigate the risk of gout related to genetic factors. METHODS: Within the UK Biobank, 416,481 gout-free...

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Genetic Predisposition to Disease
Gout
Healthy Lifestyle
Longitudinal Studies
Risk Factors

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PMID: 35484537
DOI: 10.1186/s12916-022-02341-0
PMCID: PMC9052486

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