Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploring Potential Causal Links: How Parkinson’s Disease Brain Damage Impacts Liver Health–A Mendelian Randomization and Transcriptomic Study

1 Jun 2025

Abstract excerpt

Background: Parkinson's disease (PD) is a common neurodegenerative disorder characterized by slow movements, muscle rigidity, tremors, and changes in gait and posture. Clinical studies have demonstrated a close association between PD and liver disease, but most research has focused on the impact of liver disorders on brain damage in PD, and further exploration is needed to understand the pathways and mechanisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to Neurological diseases and metabolism
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40567586
DOI: 10.2147/jir.s511645

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 28 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploring Potential Causal Links: How Parkinson’s Disease Brain Damage Impacts Liver Health–A Mendelian Randomization and Transcriptomic StudyPMID 40567586Read ↗

Serum Metabolites and Parkinson‘s Disease: A Bidirectional Mendelian Randomization StudySemantic proximity Read ↗

Identification of immune-mitophagy related gene in PD based on single-cell sequencing and Mendelian randomizationSemantic proximity Read ↗

Integrating plasma circulating protein-centered multi-omics to identify potential therapeutic targets for Parkinsonian cognitive disordersSemantic proximity Read ↗

Possible linking and treatment between Parkinson's disease and inflammatory bowel disease: a study of Mendelian randomization based on gut-brain axis.Semantic proximity Read ↗

Plasma lipidome, circulating inflammatory proteins, and Parkinson’s disease: a Mendelian randomization studySemantic proximity Read ↗

Cerebrospinal fluid and plasma metabolites in Parkinson's disease: a Mendelian randomization study.Semantic proximity Read ↗

Possible Linking and Treatment between Parkinson’s Disease and Inflammatory Bowel Disease: A Study of Mendelian Randomization Based on Gut–Brain AxisSemantic proximity Read ↗

Cerebrospinal Fluid and Plasma Metabolites with Parkinson’s Disease: A Mendelian Randomization StudySemantic proximity Read ↗

Genetic Associations of Lipid-Lowering Drugs and Parkinson’s Disease: A Mendelian Randomization StudySemantic proximity Read ↗

Methylated Cytochrome P450 and the Solute Carrier Family of Genes Correlate With Perturbations in Bile Acid Metabolism in Parkinson’s DiseaseSemantic proximity Read ↗

Comparative Proteomic Analysis of Environmental and Genetic Models of Parkinson’s Disease Highlights the Role of Purine MetabolismSemantic proximity Read ↗

Mitochondria‐Related Genome‐Wide Mendelian Randomization Identifies Putatively Causal Genes for Neurodegenerative DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.