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Article

Generation of Plexin-B1 Conditional Knockout Mouse With CRISPR/Cas9 Technology.

Genesis (New York, N.Y. : 2000) - 1 Jun 2025

Ni Haofei, Kelley Kevin, Xie Ning, Zou Hongyan, Friedel Roland H

Abstract excerpt

Plexins are axon guidance transmembrane receptors that control cytoskeleton and membrane dynamics in development and adult physiology. As plexins are expressed in multiple cell types in various tissues, floxed alleles that enable conditional deletion are needed to facilitate cell type-specific functional analysis. We report here the generation of a conditional floxed allele of Plexin-B1 (gene symbol Plxnb1) in...

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Identifiers

PMID: 40566742
DOI: 10.1002/dvg.70019
PMCID: PMC12221227

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