Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A simple and effective genotyping workflow for rapid detection of CRISPR genome editing.

American journal of physiology. Gastrointestinal and liver physiology - 1 Apr 2024

Wang Lingxiang, Wang Jiale, Feng Dongfeng, Wang Bin, Jahan-Mihan Yasmin, Wang Ying, Bi Yan, Lim DoYoung, Ji Baoan

Abstract excerpt

Genetically engineered mouse models play a pivotal role in the modeling of diseases, exploration of gene functions, and the development of novel therapies. In recent years, clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9)-mediated genome editing technology has revolutionized the process of developing such models by enabling precise genome modifications of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR-Associated Protein 9
Share to CRISPR-Cas Systems

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Editing

Share to Genotype

Share to Trypsinogen

Share to Workflow

Source

Open in PubMed Open full text

Identifiers

PMID: 38410866
DOI: 10.1152/ajpgi.00013.2024
PMCID: PMC11216750

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A simple and effective genotyping workflow for rapid detection of CRISPR genome editing.PMID 38410866Read ↗

Genotyping Protocols for Genetically Engineered Mice.Semantic proximity Read ↗

Genome editing for the reproduction and remedy of human diseases in mice.Semantic proximity Read ↗

One-Step Genotyping Method in loxP-Based Conditional Knockout Mice Generated by CRISPR-Cas9 Technology.Semantic proximity Read ↗

High-throughput genotyping of high-homology mutant mouse strains by next-generation sequencing.Semantic proximity Read ↗

Direct Generation of Conditional Alleles Using CRISPR/Cas9 in Mouse Zygotes.Semantic proximity Read ↗

Redefining mouse transgenesis with CRISPR/Cas9 genome editing technology.Semantic proximity Read ↗

A simple and practical workflow for genotyping of CRISPR-Cas9-based knockout phenotypes using multiplexed amplicon sequencing.Semantic proximity Read ↗

CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome.Semantic proximity Read ↗

Universal method for generating knockout mice in multiple genetic backgrounds using zygote electroporationSemantic proximity Read ↗

Detailed phenotypic and molecular analyses of genetically modified mice generated by CRISPR-Cas9-mediated editing.Semantic proximity Read ↗

MultiFRAGing: Rapid and Simultaneous Genotyping of Multiple Alleles in a Single Reaction.Semantic proximity Read ↗

A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular Research.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.