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Role of CDH1 gene variants and E-cadherin localization in gastric mucosal cancerization

9 May 2025

Abstract excerpt

Background This study investigates the role of CDH1 gene single nucleotide polymorphisms (SNPs), mRNA transcription levels, and E-cadherin protein localization in Helicobacter pylori (Hp)-associated gastric diseases and their contribution to gastric mucosal carcinogenesis. Methods Gastric mucosal samples were analyzed for histopathology (Hematoxylin-Eosin staining) and Hp detection (rapid urease test, Giemsa...

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PMID: 40416864
DOI: 10.3389/fonc.2025.1590680

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