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Article

Genetic predisposition to gastric cancer.

Seminars in oncology - 1 Oct 2016

Petrovchich Iva, Ford James M

Abstract excerpt

Gastric cancer ranks as the third leading cause of cancer mortality worldwide and confers a 5-year survival of 20%. While most gastric cancers are sporadic, ~1%-3% can be attributed to inherited cancer predisposition syndromes. Germline E-cadherin/CDH1 mutations have been identified in families with an autosomal dominant inherited predisposition to diffuse gastric cancer. The cumulative risk of gastric cancer for...

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Source

Identifiers

PMID: 27899187
DOI: 10.1053/j.seminoncol.2016.08.006

Genes

CDH1
CTNNA1
FBXO24
INSR
MSR1
PRSS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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