Article
CDH1 gene polymorphisms, plasma CDH1 levels and risk of gastric cancer in a Chinese population.
Molecular biology reports - 1 Aug 2012
Zhan Zhen, Wu Juan, Zhang Jun-Feng, Yang Ya-Ping, Tong Shujuan, Zhang Chun-Bing, Li Jin, Yang Xue-Wen, Dong Wei
Abstract excerpt
The genetic polymorphisms in E-cadherin gene (CDH1) may affect invasive/metastatic development of gastric cancer by altering gene transcriptional activity of epithelial cell. Our study aims to explore the associations among CDH1 gene polymorphisms, and predisposition of gastric cancer. We genotyped four potentially functional polymorphisms (rs13689, rs1801552, rs16260 and rs17690554) of the CDH1 gene in a...
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