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Liquid biopsy for the detection of H3K27m in patients with brainstem tumors.

Neurosurgical review - 26 May 2025

Gavrjushin A V, Papusha L I, Veselkov A A, Zaitseva M A, Khukhlaeva E A, Konovalov A N, Druy A E

Abstract excerpt

The treatment of diffuse brainstem tumors is prescribed in most cases without morphological or molecular genetic verification. "Liquid biopsy" is a minimally invasive technique that provides information about the biology of tumors without a standard biopsy. We set out to determine the informativeness of this diagnostic method for detecting H3K27 and BRAF V600E mutations in patients with diffuse brainstem tumors....

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PMID: 40415124
DOI: 10.1007/s10143-025-03593-z

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BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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