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Article

Detection of circulating tumor DNA in plasma of patients with primary CNS lymphoma by digital droplet PCR.

BMC cancer - 2 Apr 2024

Zhong Yujie, Tan Geok Wee, Bult Johanna, Veltmaat Nick, Plattel Wouter, Kluiver Joost, Enting Roelien, Diepstra Arjan, van den Berg Anke, Nijland Marcel

Abstract excerpt

BACKGROUND: Primary central nervous system lymphoma (PCNSL) are rare mature B-cell lymphoproliferative diseases characterized by a high incidence of MYD88 L265P and CD79B Y196 hotspot mutations. Diagnosis of PCNSL can be challenging. The aim of the study was to analyze the detection rate of the MYD88 L265P and CD79B Y196 mutation in cell free DNA (cfDNA) in plasma of patients with PCNSL. METHODS: We analyzed by...

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Identifiers

PMID: 38566053
DOI: 10.1186/s12885-024-12191-z
PMCID: PMC10985975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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