Bacterial Cells Engineered with Synthetic Genetic Materials for Blind Testing of Random Mutagenesis.

Abstract excerpt

Synthetic genetic materials, particularly those in genetically modified organisms (GMOs) deployed into complex environments, necessitate robust postmarket surveillance for continuous monitoring of both the materials and their applications throughout their lifecycle. Here, we introduce novel-coded genomic material for a blind mutation test that evaluates mutagenesis in synthetic genomic sequences without requiring...

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