Article
Chemical and UV Mutagenesis.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016
Bose Jeffrey L
Abstract excerpt
The ability to create mutations is an important step towards understanding bacterial physiology and virulence. While targeted approaches are invaluable, the ability to produce genome-wide random mutations can lead to crucial discoveries. Transposon mutagenesis is a useful approach, but many interesting mutations can be missed by these insertions that interrupt coding and noncoding sequences due to the integration...
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