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Unravelling the Impact of Outer Membrane Protein, OmpA , From S. Typhimurium on Aberrant AID Expression and IgM to IgA Class Switching in Human B‐Cells

29 Apr 2025

Abstract excerpt

Salmonella enterica serovar Typhimurium is a Gram-negative bacterium that causes gastrointestinal infection and poses significant public health risks worldwide. This study aims to explore how S. Typhimurium manipulates B-cell function through outer membrane protein A (OmpA). We investigate the effect of OmpA on Raji human B-cells, leading to the induction of activation-induced cytidine deaminase (AID) protein,...

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PMID: 40300848
DOI: 10.1111/imm.13938

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